Immunovirological discordance among female sex workers who start antiretroviral therapy in Burkina Faso

Autor: Wilfried Wenceslas Bazié, Diane Yirgnur Somé, Isidore Tiandiogo Traoré, Anselme Sanon, Issouf Konaté, Souleymane Tassembedo, Ajani Ousmane Taofiki, Dramane Kania, Abdoulaye Ouédraogo, Bea Vuylsteke, Caroline Gilbert, Nicolas Meda, Abdoul Salam Ouédraogo, Nicolas Nagot
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-10 (2022)
Druh dokumentu: article
ISSN: 1471-2334
DOI: 10.1186/s12879-022-07109-8
Popis: Abstract Background In people living with HIV/AIDS (PLWHA), initiation of antiretroviral therapy (ART) leads to sustained effective suppression of viral replication and increasing CD4 + T cell count. However, a fraction of ART-treated patients still fail to reach adequate CD4 + T cell number despite a suppressed viral load (VL), and this phenomenon is defined as immunovirological discordance (IVD). In Africa, several studies have reported immunovirological outcomes of antiretroviral therapy, but little is known about IVD occurrence in Female sex workers (FSW). This study aimed to assess the prevalence of IVD and associated factors among a cohort of HIV infected FSW in Burkina Faso. Methods We conducted a cohort study from December 2003 to October 2016. Immunovirological discordance was defined as CD4 + T cell gain
Databáze: Directory of Open Access Journals
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