Liver Histopathology in Pediatric Patients with Choledochal Cyst
| Autor: | Kumar Mayank, Subhasis Roy Choudhury, Smita Singh, Yogesh Kumar Sarin |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | Journal of Indian Association of Pediatric Surgeons, Vol 29, Iss 3, Pp 213-218 (2024) |
| Druh dokumentu: | article |
| ISSN: | 0971-9261 1998-3891 |
| DOI: | 10.4103/jiaps.jiaps_195_23 |
| Popis: | Aim: The aim is to study the various histopathological changes in the liver in pediatric patients with choledochal cyst (CC) and correlate with the presentation and type of cyst. Methods: In a prospective observational study including all pediatric patients who underwent CC excision, histopathological changes of the liver in the form of cholestasis (CHS), portal inflammation (PI), bile duct proliferation (BDP), and fibrosis were studied and graded using a scoring system. They were analyzed in relation to age, sex, symptoms, and type of the cyst. Results: All 30 patients of CC showed various degrees of histopathological changes in the liver in the form of CHS, PI, BDP, and liver fibrosis. Patients 1 years had 17/17 (100%) fusiform variety of CC (P < 0.001). Patients 1 years presented with pain abdomen (P < 0.002). Higher grades of liver fibrosis and BDP were seen in the cystic variety compared to the fusiform variety (P < 0.001). However, no significant association was found with CHS and PI (P > 1.23). Conclusions: Histopathological changes in the liver of varying grades are seen in all patients of CC. Patients of CC |
| Databáze: | Directory of Open Access Journals |
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