The footprint of SARS-COV-2 infection in neonatal late sepsis

Autor: Zahra Jamali, Najmeh Mohammadpour, Reza Sinaei, Maedeh Jafari, Fatemeh Sabzevari, Mohammad Hasannejad
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: BMC Pediatrics, Vol 24, Iss 1, Pp 1-7 (2024)
Druh dokumentu: article
ISSN: 1471-2431
DOI: 10.1186/s12887-024-04665-7
Popis: Abstract Background Predicting and finding the viral agents responsible for neonatal late-sepsis has always been challenging. Method In this cross-sectional study, which has been done from September 2020 to December 2022, 145 hospitalized neonates suspected to late-onset sepsis alongside routine sepsis workup, were also evaluated for severe acute respiratory syndrome-coronavirus-2 (SARS-COV-2) infection, by nasopharyngeal real-time polymerase chain reaction (RT-PCR) or serological tests. Result 145 neonates including 81 girls and 64 boys with a mean age of 12.3 ± 5.9 days and an average hospitalization stay of 23.1 ± 15.4 days were enrolled in the study. While 76.6% of them had negative bacterial culture, 63 patients (43.4%) showed evidence of SARS-COV-2 infection in RT-PCR or serology tests. None of the underlying factors including gender, age, and laboratory investigation had a significant relationship with SARS-COV-2 infection. Similarly, the outcomes of death and length of hospitalization were not different between the two groups with positive and negative SARS-COV-2 RT-PCR (P
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