Biochemical and histopathological changes related to the topical application of Aloe vera ointment for canine pyoderma

Autor: Ali Arbaga, Amanallah El-Bahrawy, Ahmed Elsify, Hadeer Khaled, Hany Youssef Hassan, Ahmed Kamr
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Veterinary World, Vol 14, Iss 5, Pp 1354-1362 (2021)
Druh dokumentu: article
ISSN: 0972-8988
2231-0916
DOI: 10.14202/vetworld.2021.1354-1362
Popis: Background and Aim: Pyoderma is common in dogs, and its treatment requires a novel medication rather than antibiotic therapy. This study aimed to determine the biochemical and histopathological changes associated with the topical application of Aloe vera 20% and 40% ointments, compared with gentamicin 0.1% ointment, in dogs suffering from Staphylococcus aureus pyoderma. Materials and Methods: Serum and skin samples were collected from a negative control group before inducing pyoderma and from other subdivided groups on the 3rd, 7th, 10th, and 14th days post-inoculation for biochemical and histopathology examination. Results: Serum aspartate aminotransferase, alanine aminotransferase (ALT), urea, and creatinine concentrations were higher in the positive control dogs on the 3rd day without treatment (DWT) compared with the negative control dogs (p
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