| Autor: |
Lorena Capdevila, Max T. G. M. Derks, Marc Montilla, Josep M. Luis, Jana Roithová, Xavi Ribas |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
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| Zdroj: |
ChemistryEurope, Vol 2, Iss 5, Pp n/a-n/a (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2751-4765 |
| DOI: |
10.1002/ceur.202400023 |
| Popis: |
Abstract Herein, we describe the trifluoro‐ and difluoroethoxylation of C(sp2)‐H bonds using nickel(II) complexes incorporating a model macrocyclic arene substrate. Due to the coordinative properties of the macrocyclic substrate, we were able to detect and characterize the just‐formed C(sp2)−OCH2CF3−Ni(II) species by HRMS and IRPD. DFT studies on the C(sp2)−OCH2CF3 bond formation mechanism indicate that it involves a Ni(III)/Ni(I) reductive elimination followed by oxidation to Ni(II) rather than the higher energy barrier Ni(IV)/Ni(II) reductive elimination. This mechanistic investigation deepens the versatile redox abilities of Ni compounds and might help in designing new catalysts for the 2,2,2‐trifluoroethoxylation and 2,2‐difluoroethoxylation of arene C−H bonds. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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