Mechanistic insights into antibacterial and anti-biofilm activities against multidrug-resistant microbes of SnTe nanospheres synthesized by sonochemical method

Autor: Rohitkumar M. Kannaujiya, Sunil H. Chaki, Ankurkumar J. Khimani, Ranjan Kr. Giri, Anilkumar B. Hirpara, Yati H. Vaidya, Milind P. Deshpande
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Chemical Physics Impact, Vol 6, Iss , Pp 100219- (2023)
Druh dokumentu: article
ISSN: 2667-0224
DOI: 10.1016/j.chphi.2023.100219
Popis: The sonochemical method is used to synthesize SnTe nanoparticles (Nps). Elemental analyses validated the stoichiometry of the nanoparticles. The phase and structure of the unit cell are verified by X-ray diffraction which shows nanoparticles are SnTe phase and a cubic crystal structure with a unit-cell lattice parameter of 6.31 Å having Fm-3m space group (No. 225), with Z = 4. The spherical form of nanoparticles is confirmed by electron microscopy. The Raman investigation showed a distinctive peak at 128.10 cm−1 connected to SnTe. The HR-TEM scans demonstrate that the Nps has size ranging between 25 and 30 nm and SnTe phase is confirmed by match of fringe pattern d-spacing. The SnTe Nps showed antibacterial properties through the formation of biofilms. The as-synthesized nanoparticles showed an efficient anti-microbial effect on staphylococcus aureus (MTCC 9542), listeria monocytogenes (MTCC 657), and proteus vulgaris (MTCC 426) bacteria. The study showed 100% growth suppression after 24 h of treatment with SnTe Nps, demonstrating the antimicrobial efficacy of SnTe Nps. The MIC (IC50) of 20 μg/mL for staphylococcus aureus is found to be resistant to the SnTe Nps effective anti-biofilm action. Based on these results, the authors looked into the feasibility of coating surfaces with the sample to prevent the growth of biofilms.
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