Acute Esophageal Necrosis: A View in the Dark

Autor: Hafiz Khan, Moiz Ahmed, Magda Daoud, Jobin Philipose, Saba Ahmed, Liliane Deeb
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Case Reports in Gastroenterology, Vol 13, Iss 1, Pp 25-31 (2019)
Druh dokumentu: article
ISSN: 1662-0631
00049638
DOI: 10.1159/000496385
Popis: Acute esophageal necrosis (AEN), also known as Gurvits syndrome, black esophagus, or acute necrotizing esophagitis, is a rare clinical entity and an unusual reason for upper gastrointestinal bleeding. It is typically described in critically ill patients with multiple medical conditions, arising from a combination of ischemic insult to the esophageal mucosa due to low-flow vascular states, corrosive injury caused by reflux of acid and pepsin, and decreased function of the mucosal barrier systems and reparative mechanisms as occurs in malnourished and debilitated physical states. Patients with AEN tend to be older men, as medical comorbidities including vascular disease, diabetes, hypertension, renal insufficiency, cardiac disease, pulmonary disease, stroke, and cirrhosis may be more common. Typically, patients present with upper gastrointestinal bleeding, and hematemesis or melena is seen in up to 90% of cases. Herein we present 3 cases of AEN in critically ill patients. We also provide a review of the literature to highlight what is currently known about this relatively uncommon esophageal disease.
Databáze: Directory of Open Access Journals
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