Pineal germinoma – hypogonadism issues
| Autor: | Alexandra BOLOCAN, Bogdan SOCEA, Dan N. PADURARU, Oana BOTEZAN, Octavian ANDRONIC, Andra MORAR, Cristina MOLDOVAN, Alexandra ENE, Roxana TURTUREA, Mara CARSOTE, Ana VALEA |
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| Jazyk: | English<br />French |
| Rok vydání: | 2019 |
| Předmět: | |
| Zdroj: | Archives of the Balkan Medical Union, Vol 54, Iss 4, Pp 771-775 (2019) |
| Druh dokumentu: | article |
| ISSN: | 1584-9244 2558-815X |
| DOI: | 10.31688/ABMU.2019.54.4.25 |
| Popis: | Introduction. Pineal tumors are an inhomogeneous group of lesions with pineal origin, characterized by various degrees of hypothalamic-pituitary dysfunction. Case presentation. We present the case of a patient with pineal germinoma and hypogonadotropic hypogonadism who was evaluated in several medical centers. A 31-year-old male patient with a history of primary hypothyroidism and pineal germinoma, for which he underwent surgery, radiation and chemotherapy, was admitted for frontal-temporal headache, nausea and moderate intensity asthenia. Clinical examination revealed normal weight, normal blood pressure, left eye strabismus, pale skin, diminished facial and body hair, bilateral gynecomastia. The endocrine profile showed adequate thyroid hormone replacement, low normal basal cortisol levels (5.88 µg/dL, normal 5-25 µg/dL), low IGF-1 (Insulin-like Growth Factor) (93.2 pg/mL, normal 115-307 pg/mL), low gonadotrophins, testosterone (0.57 ng/mL, normal 1.3-8.53 ng/mL) and estradiol ( |
| Databáze: | Directory of Open Access Journals |
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