| Autor: |
P Rutgeerts |
| Jazyk: |
angličtina |
| Rok vydání: |
1990 |
| Předmět: |
|
| Zdroj: |
Canadian Journal of Gastroenterology, Vol 4, Iss 7, Pp 415-416 (1990) |
| Druh dokumentu: |
article |
| ISSN: |
0835-7900 |
| DOI: |
10.1155/1990/583849 |
| Popis: |
Budesonide is a nonhalogenated glucocorticosteroid that is very suitable for topical therapy in left-sided colitis because it has a high ratio of topical to systemic activity. Although it is absorbed, it is very rapidly metabolized by the liver (first pass metabolism). It does not suppress the hypothalamic-pituitary axis. Budesonide has been shown to be more effective than placebo and predinsolone enemas for the treatment of left-sided ulcerative colitis. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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