In-vitro antidepressant property of methanol extract of Bacopa monnieri

Autor: Jawaher Alkahtani, Mohamed S. Elshikh, Yheni Dwiningsih, Muthaiyan Ahalliya Rathi, Rengasamy Sathya, P. Vijayaraghavan
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Journal of King Saud University: Science, Vol 34, Iss 8, Pp 102299- (2022)
Druh dokumentu: article
ISSN: 1018-3647
DOI: 10.1016/j.jksus.2022.102299
Popis: Objectives: The present investigation was aimed to analyze the antidepressant activity of methanol extract of Bacopa monnieri using albino rats. Methods: Three doses of methanol extract (25, 50 and 100 mg/kg), and standard (imipramine hydrochloride, 25 mg/kg) were administered to albino rats. Methanol extract was subjected to use forced swimming test, tail suspension test and locomotor activities. Results: At 25 mg/kg, 50 mg/kg and 100 mg/kg doses, immobility time decreased at 49.6%, 59.5% and 69.9%, respectively than control (p value
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