| Autor: |
Magda El Backry, Magda Shady, Amani Ezzat Mousa, Mona Mahmoud Zaky |
| Jazyk: |
angličtina |
| Rok vydání: |
2015 |
| Předmět: |
|
| Zdroj: |
The Egyptian Journal of Radiology and Nuclear Medicine, Vol 46, Iss 3, Pp 715-726 (2015) |
| Druh dokumentu: |
article |
| ISSN: |
0378-603X |
| DOI: |
10.1016/j.ejrnm.2015.01.001 |
| Popis: |
Aim: Evaluation of diagnostic accuracy of dynamic contrast enhanced (DCE) MRI in differentiating benign from malignant head and neck tumors using both Quantitative and semi quantitative analysis. Patients and methods: 55 patients with head and neck masses underwent DCEMRI at 1.5 T Philips Ingenia MR scanner. Their enhancement curve patterns, Time to peak, wash in and washout rates were analyzed and compared in benign and malignant tumors. Results: 81.8% of benign tumors had gradual progressing and plateau curves, while 93.3% of malignant tumors had plateau and fast curves. TTP, wash in and wash out rates were significantly different between benign and malignant tumors. Using TTP cut off value of 83.3 s differentiated benign from malignant tumors with a sensitivity of 84.8% and specificity of 77.3%, while wash in rate at cut off value of 15.4 1/s provided a sensitivity of 87.9% and specificity of 90.9%, wash out rates provided at cut off value of 5.75 1/s, a sensitivity of 81.8% and specificity of 90.9%. Conclusion: Dynamic contrast enhanced MRI is a promising method for differentiation between benign and malignant head and neck tumors, wash in rate is the most specific parameter used. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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