Autor: |
Luca P. Weltert, Katia Audisio, Michele La Torre, Michele Dell’Aquila, Gianmarco Cancelli, Vittoria Lodo, Tulio Caldonazo, Camilla S. Rossi, Giovanni J. Soletti, Luigi Garufi, Paolo Centofanti, Ruggero De Paulis, Mauro Rinaldi |
Jazyk: |
angličtina |
Rok vydání: |
2024 |
Předmět: |
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Zdroj: |
BMC Cardiovascular Disorders, Vol 24, Iss 1, Pp 1-7 (2024) |
Druh dokumentu: |
article |
ISSN: |
1471-2261 |
DOI: |
10.1186/s12872-024-04237-8 |
Popis: |
Abstract Background The impact of air bubbles into the cerebral circulation after open heart surgery has been a topic of discussion since the introduction of the heart-lung machine. The aim of the study was to evaluate whether the use of a dedicated commercial sponge diffuser is better than a custom-made narrow section cannula or the absence of CO2 in preventing neurological events after aortic valve replacement via J mini-sternotomy. Methods Three cohorts of J-shaped mini-sternotomy performed at three different centers were prospectively compared: CO2 supplied via sponge diffuser, CO2 supplied via cannula, and no CO2 supply. Propensity matching was used to obtain comparable groups. The primary endpoints were postoperative stroke, transitory ischemic attack, convulsions, and dizziness. Secondary endpoints were 30-day mortality, duration of mechanical ventilation, and intensive care unit length of stay. Results 275 patients were enrolled in the study. After propensity matching, the sponge diffuser cohort had a significantly lower duration of mechanical ventilation (P |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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