Patient Blood Management improves outcome in oncologic surgery

Autor: Vivienne Keding, Kai Zacharowski, Wolf O. Bechstein, Patrick Meybohm, Andreas A. Schnitzbauer
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: World Journal of Surgical Oncology, Vol 16, Iss 1, Pp 1-7 (2018)
Druh dokumentu: article
ISSN: 1477-7819
DOI: 10.1186/s12957-018-1456-9
Popis: Abstract Background Patient Blood Management (PBM) is a systematic quality improving clinical model to reduce anemia and avoid transfusions in all kinds of clinical settings. Here, we investigated the potential of PBM in oncologic surgery and hypothesized that PBM improves 2-year overall survival (OS). Methods Retrospective analysis of patients 2 years before and after PBM implementation. The primary endpoint was OS at 2 years after surgery. We identified a sample size of 824 to detect a 10% improvement in survival in the PBM group. Results The analysis comprised of 836 patients that underwent oncologic surgery, 389 before and 447 after PBM, was implemented. Patients in the PBM+ presented significantly more frequent with normal hemoglobin values before surgery than PBM− (56.6 vs. 35.7%; p 12 g/dl in female and > 13 g/dl in male) before surgery (HR 0.43, 95% CI 0.29–0.65, p
Databáze: Directory of Open Access Journals
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