| Autor: |
Alejandro Castán, Ramón Badorrey, José A. Gálvez, María D. Díaz-de-Villegas |
| Jazyk: |
angličtina |
| Rok vydání: |
2017 |
| Předmět: |
|
| Zdroj: |
Beilstein Journal of Organic Chemistry, Vol 13, Iss 1, Pp 612-619 (2017) |
| Druh dokumentu: |
article |
| ISSN: |
1860-5397 |
| DOI: |
10.3762/bjoc.13.59 |
| Popis: |
New pyrrolidine-based organocatalysts with a bulky substituent at C2 were synthesized from chiral imines derived from (R)-glyceraldehyde acetonide by diastereoselective allylation followed by a sequential hydrozirconation/iodination reaction. The new compounds were found to be effective organocatalysts for the Michael addition of aldehydes to nitroolefins and enantioselectivities up to 85% ee were achieved. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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