Prevalance of Celiac Disease in Subjects With Diverticular Disease Of The Colon

Autor: Mesut Aydın, Serhat Özer, Yaren Dirik, Elif Tuğba Tuncel, Ahmet Cumhur Dülger
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Van Tıp Dergisi, Vol 28, Iss 3, Pp 400-403 (2021)
Druh dokumentu: article
ISSN: 2587-0351
DOI: 10.5505/vtd.2021.53323
Popis: INTRODUCTION: Celiac disease (CD) is a small bowel malabsorption syndrome that is caused by hypersensitivity to wheat in subjects who have positive HLA haplotypes DQ2 and DQ8. Diverticular disease of the colon (DDC) is saccular dilatations of colon, which is seen mostly in adults older than 40. In this study, we tried to see whether CD is protective for DDC. METHODS: We identified 114 (57 female; the mean age 58+-4.1 years) patients with DDC during the 7-month period from January to October 2018. Age-matched control group (100 subjects; 50 female; the mean age 59+-3.4 years) was selected from subjects without DDC. RESULTS: Among subjects with DDC, only one tested positive for CD serologically (Tissue Transglutaminase - tTTG IgA and G). In control subjects with dyspepsia, 2.8% of subjects tested positive for celiac antibodies. There was a robust difference between groups in terms of TTG Ig A seropositivity (P
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