| Autor: |
Jin Gong, Shaoqi Li, Wenxian Sun, Pin Wang, Xiaodong Han, Chang Xu, Yufei Chen, Yuting Yang, Heya Luan, Ruina Li, Boye Wen, Sirong Lv, Runqi Chen, Jinxuan Guo, Cuibai Wei |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
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| Zdroj: |
Stem Cell Research, Vol 79, Iss , Pp 103501- (2024) |
| Druh dokumentu: |
article |
| ISSN: |
1873-5061 |
| DOI: |
10.1016/j.scr.2024.103501 |
| Popis: |
Apolipoprotein E (APOE)is the gene with greatest genetic risk for Alzheimer’s disease (AD). We successfully established a human induced pluripotent stem cell(iPSC) line from a woman mutated by APOE gene. The cell line was isolated from this woman’s peripheral blood mononuclear cells using a non-integrated Sendai virus, which retained the original genotype, showed a normal karyotype, highly expressed pluripotent markers and could differentiate into three germ layers. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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