Intrauterine onset of multisystem inflammatory syndrome in a neonate temporally associated with maternal COVID-19

Autor:	U S Nitya, Brinda M Devassy, Shiji Joseph, A P Anila, Rupesh George, V K Sreenivasan
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	coronavirus infectious disease antibody cytokine storm multisystem inflammatory syndrome in children multisystem inflammatory syndrome in neonates neonates prolonged corrected qt interval severe acute respiratory syndrome-coronavirus-2 Diseases of the musculoskeletal system RC925-935
Zdroj:	Indian Journal of Rheumatology, Vol 17, Iss 3, Pp 289-293 (2022)
Druh dokumentu:	article
ISSN:	0973-3698 0973-3701
DOI:	10.4103/injr.injr_4_22
Popis:	Multisystem inflammatory syndrome in children (MIS-C) associated with COVID-19 is a rare but often life-threatening clinical entity that presents 3–6 weeks after SARS-CoV-2 infection with high fever, organ dysfunction, and strongly elevated markers of inflammation. Unlike MIS-C, where SARS-CoV-2 infection and multisystem inflammation occur in the same subject, maternal SARS-CoV-2 infection may cause a similar hyperinflammatory syndrome in neonates called multisystem inflammatory syndrome in neonates (MIS-N) due to transplacental transfer of antibodies. The clinical profile of these babies remains obscure due to a lack of published literature. Our case highlights the need for practicing pediatricians to be vigilant and to have a high index of clinical suspicion of MIS-N in all critically ill neonates irrespective of antenatal COVID-19 status of mother.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/495a083c9243412db957f4dff33b500e Zobrazit plný text záznamu View record in DOAJ