Young‐onset type 2 diabetes mellitus enhances proteinuria, but not glomerular filtration rate decline: A Japanese cohort study

Autor:	Haruka Saito, Hayato Tanabe, Hiroyuki Hirai, Moritake Higa, Kenichi Tanaka, Satoshi Yamaguchi, Gulinu Maimaituxun, Hiroaki Masuzaki, Junichiro J Kazama, Michio Shimabukuro
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	Diabetic kidney disease Proteinuria Young‐onset diabetes Diseases of the endocrine glands. Clinical endocrinology RC648-665
Zdroj:	Journal of Diabetes Investigation, Vol 15, Iss 10, Pp 1444-1456 (2024)
Druh dokumentu:	article
ISSN:	2040-1124 2040-1116
DOI:	10.1111/jdi.14272
Popis:	ABSTRACT Aims/Introduction The time course of chronic kidney disease in young‐onset type 2 diabetes mellitus remains unclear. We compared the trajectories of proteinuria and estimated glomerular filtration rate (eGFR) decline between young‐onset (aged ≤40 years) and late‐onset (aged >40 years) type 2 diabetes mellitus in a Japanese multicenter cohort. Materials and Methods Participants without diabetic kidney disease were divided into two groups according to age at diagnosis: young‐ and late‐onset. The primary endpoint was eGFR
Databáze:	Directory of Open Access Journals
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