Development and validation of a nomogram to predict the five-year risk of revascularization for non-culprit lesion progression in STEMI patients after primary PCI

Autor: Feng Dai, Xianzhi Xu, Chunxue Zhou, Cheng Li, Zhaoxuan Tian, Zhaokai Wang, Shuping Yang, Gege Liao, Xiangxiang Shi, Lili Wang, Dongye Li, Xiancun Hou, Junhong Chen, Tongda Xu
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Druh dokumentu: article
ISSN: 2297-055X
DOI: 10.3389/fcvm.2023.1275710
Popis: BackgroundAcute ST-segment elevation myocardial infarction (STEMI) patients after primary PCI were readmitted for revascularization due to non-culprit lesion (NCL) progression.ObjectiveTo develop and validate a nomogram that can accurately predict the likelihood of NCL progression revascularization in STEMI patients following primary PCI.MethodsThe study enrolled 1,612 STEMI patients after primary PCI in our hospital from June 2009 to June 2018. Patients were randomly divided into training and validation sets in a 7:3 ratio. The independent risk factors were determined by LASSO regression and multivariable logistic regression analysis. Multivariate logistic regression analysis was utilized to develop a nomogram, which was then evaluated for its performance using the concordance statistics, calibration plots, and decision curve analysis (DCA).ResultsThe nomogram was composed of five predictors, including age (OR: 1.007 95% CI: 1.005–1.009, P
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