Amyloïdosis, sarcoidosis and systemic lupus erythematosus

Autor: Amel Rezgui, Imene Ben Hassine, Monia, Fatma Ben Fredj, Chadia Laouani
Jazyk: English<br />French
Rok vydání: 2016
Předmět:
Zdroj: The Pan African Medical Journal, Vol 24, Iss 23 (2016)
Druh dokumentu: article
ISSN: 1937-8688
DOI: 10.11604/pamj.2016.24.23.8853
Popis: The occurrence of renal and multiple organ Amyloïdosis is currently considered exceptional in the course of systemic lupus erythematosus. We report a case of a concomitant SLE and Amyloïdosis in a 57 year old female patient with hypothyroidism history, who presented with erythema nodosum, fever, arthralgia and sicca syndrome. Biological findings showed an inflammatory syndrome, renal failure, proteinuria (1g / 24h), positive auto antibodies and anti DNA. Lung radiology revealed medistinal lymphadenopathy, pleural nodules, ground glass infiltrates and pleuritis. Bronchial biopsy showed non specific inflammation. The salivary gland biopsy showed amyloïd deposits. This case report reminds us that lupus and Amyloïdosis association, although exceptional remains possible. The occurrence of Lofgren syndrome in this situation make the originality of this report.
Databáze: Directory of Open Access Journals