Impact of long-lasting insecticidal nets on prevalence of subclinical malaria among children in the presence of pyrethroid resistance in Anopheles culicifacies in Central India
| Autor: | Mehul Kumar Chourasia, Raghavendra Kamaraju, Immo Kleinschmidt, Rajendra M. Bhatt, Dipak Kumar Swain, Tessa Bellamy Knox, Neena Valecha |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: | |
| Zdroj: | International Journal of Infectious Diseases, Vol 57, Iss C, Pp 123-129 (2017) |
| Druh dokumentu: | article |
| ISSN: | 1201-9712 1878-3511 |
| DOI: | 10.1016/j.ijid.2017.02.001 |
| Popis: | Background: Subclinical (asymptomatic) cases of malaria could be a major barrier to the success of malaria elimination programs. This study has evaluated the impact of long-lasting insecticidal nets (LLINs) on the prevalence of subclinical malaria in the presence of pyrethroid resistance in the main malaria vector Anopheles culicifacies on malaria transmission among a cohort of children in villages of the Keshkal sub-district in Chhattisgarh state. Methods: A cohort of 6582 children ages less than 14 years was enrolled from 80 study clusters. Post monsoon survey was carried out at baseline before LLIN distribution, and 5862 children were followed up in the subsequent year. Study outcomes included assessment of subclinical malarial infections and use of LLINs among the study cohort in the presence of varied levels of pyrethroid resistance. Findings: In the baseline survey, the proportion of subclinical malaria was 6·1%. LLIN use during the previous night was 94·8%. Overall, prevalence of subclinical malaria was significantly reduced to 1% (p |
| Databáze: | Directory of Open Access Journals |
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