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Mebrahtu Gebreslassie Kidanu,1 Engdaeshet Tazebe,2 Alemseged Berhane Tesfa,2 Marta Yemane Hadush,2 Mebrihit M Kahsay,3 Mebrahtu G Tedla4 1Department of Pediatrics and Child Health, Aksum University, Aksum, Tigray, Ethiopia; 2Department of Pediatrics and Child Health, Mekelle University, Mekelle, Tigray, Ethiopia; 3College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia; 4Department of Pediatrics, School of Medicine, University of Missouri-Columbia, Columbia, MO, 65211, USACorrespondence: Mebrahtu Gebreslassie Kidanu, Department of Pediatrics and Child health, Aksum University, Aksum, Tigray, Ethiopia, Email mebrahtugeb2007@gmail.comBackground: Pediatric shock is a potentially fatal illness which develops after a systemic circulatory system failure in children. It appears to be a common emergency in children and produces substantial morbidity and mortality particularly if there is no early identification and therapy. The extent and causes of shock-induced death among children in Ethiopia have not been sufficiently studied.Objective: This study was conducted to evaluate the magnitude, determinants and short-term outcome of shock in pediatric patients who visited Ayder Comprehensive Specialized Hospital in Tigray, Northern Ethiopia.Methods: From October 1, 2020, to July 30, 2022, an observational cross-sectional study was carried out at Ayder Comprehensive Specialized Hospital. The study included 132 children from the age of 1 month to 18 years. According to pediatric advanced life support guidelines, shock was diagnosed among patients. To gather information, a pretested questionnaire was employed. To examine the relationship between the independent variables and shock outcome, bivariate logistic regression was performed, and statistical significance was defined as a P-value of 0.05 or lower.Results: The prevalence of shock was 2.2%. This study revealed 70.5% decompensated stage of shock. Mortality rate of shock was 45.5% (95% CI: 37.1– 53.8). A delayed presentation by more than one week with an adjusted odd ratio (AOR) of 16.9 (95% CI: 2.3– 123), type of shock other than hypovolemic shock with AOR of 8.3 (95% CI: 1.4– 48), stage of shock with AOR of 27.8 (95% CI: 2.8– 157), requirement of mechanical ventilation with AOR of 11 (95% CI: 2.6– 53) and length of hospital stay less than three days with AOR of 9 (95% CI: 1.7– 48) were identified as a predictor of mortality by shock in children.Conclusion: According to this study, shock causes a high rate of child mortality. Independent predictors of mortality included delayed presentation, shock type, stage of shock, the need for mechanical ventilation, and brief hospital stay (less than three days).Keywords: shock, children, cross-sectional study, Ayder Hospital |
