Role of ureteral stent material and coating to prevent ureteral stent related issue: A systematic review and meta analysis

Autor: Ignatius Ivan Putrantyo, Syah Mirsya Warli, Ginanda Putra Siregar, Fauriski Febrian Prapiska, Dhirajaya Dharma Kadar, Bungaran Sihombing
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Archivio Italiano di Urologia e Andrologia (2024)
Druh dokumentu: article
ISSN: 1124-3562
2282-4197
DOI: 10.4081/aiua.2024.12067
Popis: Introduction: Ureteral stents require materials that balance bulk and surface properties. Achieving both can be challenging, as ideal bulk properties may not align with optimal surface properties. Thus, researching coatings and biomanufacturing methods for ideal materials is essential. Methods: A systematic review and meta-analysis, following PRISMA Guidelines, involved literature searches across five databases: PubMed, Scopus, Embase, ClinicalKey, and Cochrane. From 417 screened articles, eight studies were deemed eligible for qualitative and quantitative analysis. The selected articles underwent bias assessment using ROB Tools 2. Results: The systematic review analyzed 1.356 participants. Findings revealed that firm ureteral stents significantly increased risk of infection, hematuria, and lower body pain. On the contrary, soft stents reduced infection (OR: 0.62; p = 0.004), hematuria (OR: 0.60; p = < 0.001), and lower body pain (OR: 0.63; p = 0.0002). However, infection reduction effect was uncertain due to heterogeneity. Coated vs. non-coated material analysis found no difference in encrustation (OR: 1.26; p = 0.52) or infection (OR: 1.67; p = 0.99). Stent firmness didn't affect encrustation on double J stent (OR: 0.97; p = 0.17). Conclusions: Softer materials like silicone are preferred for ureteral stents to reduce symptoms like hematuria and lower body pain. Coatings like silver nanoparticles and triclosan, while enhancing antimicrobial properties, didn't effectively lower infection risk.
Databáze: Directory of Open Access Journals
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