Booster with Ad26.COV2.S or Omicron-adapted vaccine enhanced immunity and efficacy against SARS-CoV-2 Omicron in macaques

Autor: Laura Solforosi, Lea M. M. Costes, Jeroen T. B. M. Tolboom, Katherine McMahan, Tochi Anioke, David Hope, Tetyana Murdza, Michaela Sciacca, Emily Bouffard, Julia Barrett, Cindy Wu, Nicole Hachmann, Jessica Miller, Jingyou Yu, Xuan He, Catherine Jacob-Dolan, Sietske K. Rosendahl Huber, Liesbeth Dekking, Ronnie Chamanza, Ying Choi, Karin Feddes-de Boer, Dan H. Barouch, Hanneke Schuitemaker, Roland C. Zahn, Frank Wegmann
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-023-37715-2
Popis: Variant booster vaccines are a strategy to improve protection against SARS-CoV-2. Here, the authors find that both Wuhan-Hu-1-based Ad26.COV2.S or an Omicron-adapted booster vaccine provide robust immune responses and protection against Omicron in NHP.
Databáze: Directory of Open Access Journals