Survival in elderly patients with breast cancer with and without autoimmune disease

Autor:	Demitrios Dedousis, Annie L. Zhang, Anastasia N. Vassiliou, Shufen Cao, Deepthi Yammani, Ravi K. Kyasaram, John P. Shanahan, Melissa C. Keinath, Melinda L. Hsu, Pingfu Fu, Afshin Dowlati, Alberto J. Montero
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	autoimmune diseases breast neoplasms Medicare statistics & numerical data prevalence SEER program survival analysis Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Zdroj:	Cancer Medicine, Vol 12, Iss 12, Pp 13086-13099 (2023)
Druh dokumentu:	article
ISSN:	2045-7634
DOI:	10.1002/cam4.5989
Popis:	Abstract Background Patients with certain autoimmune conditions are at a reduced risk of developing breast cancer compared to the general population. Despite this, little is known about outcomes in patients with breast cancer who have a concurrent autoimmune diagnosis. Methods This study compared differences in outcomes between women with breast cancer who had or did not have an autoimmune diagnosis. The SEER‐Medicare databases (2007–2014) were used to identify patients with breast cancer and diagnosis codes were used to identify those with an autoimmune disorder. Results The studied autoimmune diseases had a prevalence of 27% among the 137,324 patients with breast cancer. Autoimmune disease was associated with significantly longer overall survival (OS) and significantly lower cancer‐specific mortality (CSM) among stage IV breast cancer patients (p
Databáze:	Directory of Open Access Journals
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