| Autor: |
Katerina Vlahos, Koula Sourris, Robyn Mayberry, Penelope McDonald, Freya F. Bruveris, Jacqueline V. Schiesser, Kiymet Bozaoglu, Paul J. Lockhart, Edouard G. Stanley, Andrew G. Elefanty |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
Stem Cell Research, Vol 34, Iss , Pp - (2019) |
| Druh dokumentu: |
article |
| ISSN: |
1873-5061 |
| DOI: |
10.1016/j.scr.2018.101380 |
| Popis: |
Abstract: We describe the generation and characterization of 5 human induced pluripotent stem cell (iPSC) lines derived from peripheral blood mononuclear cells (PBMCs) of healthy adult individuals. The PBMCs were reprogrammed using non-integrating Sendai viruses containing the reprogramming factors POU5F1 (OCT4), SOX2, KLF4 and MYC. The iPSC lines exhibited a normal karyotype, expressed pluripotency markers and differentiated into cells representative of the three embryonic germ layers. These iPSC lines can be used as controls in studying disease mechanisms. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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