Dupilumab-associated sezary syndrome

Autor: Austin Hamp, Jamie Hanson, Albert Alhatem, Robert A Schwartz
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Indian Journal of Dermatology, Vol 68, Iss 4, Pp 459-462 (2023)
Druh dokumentu: article
ISSN: 0019-5154
1998-3611
DOI: 10.4103/ijd.ijd_580_22
Popis: Dupilumab is a monoclonal antibody that inhibits interleukin-4 (IL-4) and interleukin-13 (IL-13), approved for the treatment of adults with moderate-to-severe atopic dermatitis (AD). While recent reports have described cases of new-onset mycosis fungoides (MF) following treatment with dupilumab for AD, to our knowledge only one patient has been delineated with the progression to SS. We present an additional case of a patient who was diagnosed with SS following treatment with dupilumab for adult-onset AD and asthma. We examine SS as a possible side effect of dupilumab while also discussing management and theories to explain this phenomenon.
Databáze: Directory of Open Access Journals
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