Cardiac Arrest-Associated Coagulopathy Could Predict 30-day Mortality: A Retrospective Study from Medical Information Mart for Intensive Care IV Database

Autor: Jingwei Duan MD, Hongxia Ge MD, Wenyang Fan MS, Lanfang Du MD, Hua Zhang PhD, Ayijiang Jiamaliding MD, Baomin Duan MS, Qingbian Ma MD
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Clinical and Applied Thrombosis/Hemostasis, Vol 30 (2024)
Druh dokumentu: article
ISSN: 1938-2723
10760296
DOI: 10.1177/10760296231221986
Popis: Background Cardiac arrest (CA) can activate the coagulation system. Some coagulation-related indicators are associated with clinical outcomes. Early evaluation of patients with cardiac arrest-associated coagulopathy (CAAC) not only predicts clinical outcomes, but also allows for timely clinical intervention to prevent disseminated intravascular coagulation. Objective To assess whether CAAC predicts 30-day cumulative mortality. Methods From the Medical Information Mart for Intensive Care IV (MIMIC-IV) database, we conducted a retrospective cohort study from 2008 to 2019. Based on international normalized ratio (INR) value and platelet count, we diagnosed CAAC cases and made the following stratification of severity: mild CAAC was defined as 1.4 > INR≧1.2 and 100,000/µL INR≧1.4 or 80,000/µL
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