NUT carcinoma of the head and neck: A case report and literature review

Autor: Yue Zhao, Jun Zhang, Wenjun Liao, Jiayu Li, Shichuan Zhang
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Precision Radiation Oncology, Vol 8, Iss 3, Pp 138-144 (2024)
Druh dokumentu: article
ISSN: 2398-7324
DOI: 10.1002/pro6.1237
Popis: Abstract Nuclear protein in testis (NUT) carcinoma is a rare and highly aggressive cancer, characterized by rearrangements involving the NUT gene located on chromosome 15q14. In this report, we present the case of a 52‐year‐old female diagnosed with primary parotid NUT carcinoma. Despite undergoing surgery, adjuvant chemotherapy, and incomplete regional radiotherapy, the patient succumbed to the disease after an overall survival duration of 7 months. We retrospectively discuss patient clinical and pathological features, as well as therapeutic approaches of NUT carcinoma of the head and neck.
Databáze: Directory of Open Access Journals