Investigation of corneal topographic and densitometric properties of Wilson's disease patients with or without a Kayser-Fleischer ring

Autor: Mehmet Fuat Alakus, Mehtap Caglayan, Nazım Ekin, Hasan Oncul, Esref Arac, Umut Dag, Halit Diri
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Eye and Vision, Vol 8, Iss 1, Pp 1-8 (2021)
Druh dokumentu: article
ISSN: 2326-0254
DOI: 10.1186/s40662-021-00231-9
Popis: Abstract Background To investigate the topographic measurements and densitometry of corneas in Wilson’s disease (WD) patients with or without a Kayser-Fleischer ring (KF-r) compared to healthy individuals. Methods This cross-sectional study included 20 WD patients without a KF-r (group I), 18 WD patients with a KF-r (group II), and 20 age-matched controls (group III). The Pentacam high resolution imaging system is used to determine corneal topographic measurements and densitometry. Results Mean age for groups I, II and III was 25.40 ± 6.43 years (14–36 years), 25.38 ± 6.96 years (16–39 years), 23.60 ± 6.56 years (17–35 years), respectively (P = 0.623). There was no significant difference between the groups in terms of the anterior corneal densitometry values (P > 0.05), while the 6–10 mm and 10–12 mm mid stroma and the 2–6 mm, 6–10 mm, and 10–12 mm posterior corneal densitometry values in group II were significantly higher than those in groups I and III (for all values, P
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