Cell Densities in the Mouse Brain: A Systematic Review

Autor: Daniel Keller, Csaba Erö, Henry Markram
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Frontiers in Neuroanatomy, Vol 12 (2018)
Druh dokumentu: article
ISSN: 1662-5129
DOI: 10.3389/fnana.2018.00083
Popis: The mouse brain is the most extensively studied brain of all species. We performed an exhaustive review of the literature to establish our current state of knowledge on cell numbers in mouse brain regions, arguably the most fundamental property to measure when attempting to understand a brain. The synthesized information, collected in one place, can be used by both theorists and experimentalists. Although for commonly-studied regions cell densities could be obtained for principal cell types, overall we know very little about how many cells are present in most brain regions and even less about cell-type specific densities. There is also substantial variation in cell density values obtained from different sources. This suggests that we need a new approach to obtain cell density datasets for the mouse brain.
Databáze: Directory of Open Access Journals