Clinical outcome of skin yaws lesions after treatment with benzathinebenzylpenicillin in a pygmy population in Lobaye, Central African Republic

Autor: Manirakiza Alexandre, Boas Susana, Beyam Narcisse, Zadanga Germain, Konamna François, Njuimo Siméon P, Laganier Rémi
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Zdroj: BMC Research Notes, Vol 4, Iss 1, p 543 (2011)
Druh dokumentu: article
ISSN: 1756-0500
48843164
DOI: 10.1186/1756-0500-4-543
Popis: Abstract Background Yaws is a bacterial skin and bone infectious disease caused by Treponema pallidum pertenue. It is endemic, particularly among pygmies in Central African Republic. To assess the clinical cure rate after treatment with benzathinepenicillin in this population, we conducted a cohort survey of 243 patients in the Lobaye region. Findings and conclusion The rate of healing of lesions after 5 months was 95.9%. This relatively satisfactory level of therapeutic response implies that yaws could be controlled in the Central African Republic. Thus, reinforcement of the management of new cases and of contacts is suggested.
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