| Autor: |
Đan I., Stokić Edita, Sakač D., Đan Mihajla, Obreht Dragana, Erak M., Jovanović Nataša |
| Jazyk: |
angličtina |
| Rok vydání: |
2011 |
| Předmět: |
|
| Zdroj: |
Archives of Biological Sciences, Vol 63, Iss 1, Pp 89-98 (2011) |
| Druh dokumentu: |
article |
| ISSN: |
0354-4664 |
| DOI: |
10.2298/ABS1101089D |
| Popis: |
Apolipoprotein E displays polymorphism with three common alleles, e2, e3, and e4. The aim of this research was to determine apoE gene polymorphism in a group of healthy patients and a group of patients with CHD, and to reveal the relation between anthropometric and biochemical parameters and the apoE genotype. In CHD group significantly higher values of blood pressure, waist circumference, BMI and fat %, triglycerides, insulin (HOMA IR) and CRP were found. A statistically significant higher presence of the e3e4 genotype and e4 allele was detected in the CHD group. Statistically significant differences between waist circumference, BMI, insulin and HOMA IR were found between subjects with e3e3 and e3e4 genotypes. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
