Chemical Constituents of the Culture Broth of Panus rudis

Autor: Ja-Gyeong Song, Lee Su Ha, Dae-Won Ki, Dae-Cheol Choi, In-Kyoung Lee, Bong-Sik Yun
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Mycobiology, Vol 49, Iss 6, Pp 604-606 (2021)
Druh dokumentu: article
ISSN: 1229-8093
2092-9323
12298093
DOI: 10.1080/12298093.2021.2004663
Popis: In our ongoing search for new secondary metabolites from fungal strains, one novel compound (1) and nine known compounds (2-10) were isolated from the EtOAc-soluble layer of the culture broth of Panus rudis. The culture broth of P. rudis was extracted in acetone and fractionated by solvent partition; column chromatography using silica gel, Sephadex LH-20, and Sephadex G-10; MPLC; and HPLC. The structures of isolated compounds were elucidated by one- and two-dimensional NMR and LC-ESI-mass measurements. One new compound, panepoxydiol (1), and nine known compounds, (E)-3-(3-hydroxy-3-methylbut-1-en-1-yl)-7-oxabicyclo[4.1.0]hept-3-ene-2,5-diol (2), isopanepoxydone (3), neopanepoxydone (4), panepoxydone (5), panepophenanthrin (6), 4-hydroxy-2,2-dimethyl-6-methoxychromane (7), 6-hydroxy-2,2-dimethyl-3-chromen (8), 2,2-dimethyl-6-methoxychroman-4-one (9), 3,4-dihydroxy-2,2-dimethyl-6-methoxychromane (10), were isolated from the culture broth of P. rudis. This is the first report of isolation of a new compound panepoxydiol (1) and nine other chemical constituents (2-5, 7-10) from the culture broth of P. rudis.
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