A rare case of double-antibody-positive renal vasculitis: Are we in a hurry to start tuberculosis medicines?
| Autor: | Sunil Kumar, Ankita Kumari, Jimit N Mistry, Mohit Naredi, Ayushi Chander |
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| Jazyk: | angličtina |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | Journal of Advanced Lung Health, Vol 4, Iss 2, Pp 95-98 (2024) |
| Druh dokumentu: | article |
| ISSN: | 2772-7165 2772-7173 |
| DOI: | 10.4103/jalh.jalh_27_23 |
| Popis: | Double antibody positive renal vasculitis (anti GBM antibody and pANCA) is a rare form of small vessel vasculitis associated with poor outcome. It is difficult to decide which antibody is the precursor in these cases. We report here such a rare case of double antibody positive renal vasculitis which was started on anti tubercular medicine for a positive mantoux test and interferon gamma release assay. The possible reasons for these antibodies in this may be a complication of COVID-19 infection or vaccine, adverse drug effect of antitubercular medicines or a paradoxical reaction during the tuberculosis treatment. The patient could not survive beyond two months of diagnosis because of rapidly declining renal functions. This case highlights the importance of a meticulous clinical approach, supports two week tuberculosis medicines trial and an early and careful dealing of non responders during tuberculosis treatment especially in patients whose diagnosis is not microbiologically confirmed. |
| Databáze: | Directory of Open Access Journals |
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