The development of microfabricated solenoids with magnetic cores for micromagnetic neural stimulation

Autor: Adam Khalifa, Mohsen Zaeimbashi, Tony X. Zhou, Seyed Mahdi Abrishami, Neville Sun, Seunghyun Park, Tamara Šumarac, Jason Qu, Inbar Zohar, Amir Yacoby, Sydney Cash, Nian X. Sun
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Microsystems & Nanoengineering, Vol 7, Iss 1, Pp 1-10 (2021)
Druh dokumentu: article
ISSN: 2055-7434
DOI: 10.1038/s41378-021-00320-8
Popis: Abstract Electrical stimulation via invasive microelectrodes is commonly used to treat a wide range of neurological and psychiatric conditions. Despite its remarkable success, the stimulation performance is not sustainable since the electrodes become encapsulated by gliosis due to foreign body reactions. Magnetic stimulation overcomes these limitations by eliminating the need for a metal-electrode contact. Here, we demonstrate a novel microfabricated solenoid inductor (80 µm × 40 µm) with a magnetic core that can activate neuronal tissue. The characterization and proof-of-concept of the device raise the possibility that micromagnetic stimulation solenoids that are small enough to be implanted within the brain may prove to be an effective alternative to existing electrode-based stimulation devices for chronic neural interfacing applications.
Databáze: Directory of Open Access Journals