Association of interleukin-17A rs2275913 polymorphism with rheumatoid arthritis susceptibility in Sudanese population

Autor: Rgda Mohamed Osman, Mounkaila Noma, Abdallah Elssir Ahmed, Hanadi Abdelbagi, Rihab Ali Omer, Musab M Ali, Ayman Ali Mohammed Alameen, Ali Mahmoud Edris, Mohamed S. Muneer, Omayma Siddig, Rowa Hassan, Eiman Siddig Ahmed, Lamis Ahmed Hassan, Osama El Hadi Bakheet, Ayman Ahmed, Nouh Saad Mohamed, Emmanuel Edwar Siddig
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: SAGE Open Medicine, Vol 9 (2021)
Druh dokumentu: article
ISSN: 2050-3121
20503121
DOI: 10.1177/20503121211020207
Popis: Objectives: Rheumatoid arthritis is a chronic inflammatory autoimmune disease. This study aimed to determine the association of interleukin-17A-197G/A polymorphism with rheumatoid arthritis in Sudanese patients. Methods: A case–control study was conducted between March and December 2018. Clinical and demographic data of the study participants were collected and analyzed. Polymerase chain reaction restriction fragment length polymorphism molecular technique was done to investigate interleukin-17A-197G/A polymorphisms. All statistical tests were considered statistically significant when p
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