One-pot Synthesis of Substituted Benzimidazole Derivatives under Ultrasonic Irradiation Using ZnFe2O4 Reusable Catalyst

Autor: Dhanraj Kamble, Anil Shankarwar, Yuvraj Sarnikar, Radhakrushna Tigote, Mubarak Shaikh, Pravin Chavan
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry, Vol 17, Iss 2, Pp 94-100 (2022)
Druh dokumentu: article
ISSN: 1857-1727
2345-1688
DOI: 10.19261/cjm.2022.892
Popis: Herein, an efficient one-pot synthesis is described, of substituted benzimidazole derivatives (3a-j) from a condensation of various o-phenylenediamine (1a-j) aromatic aldehyde (2a-j) using ZnFe2O4 as a nano-catalyst under ultrasonic irradiation conditions. All forms of aldehydes with an electron releasing or electron –withdrawing substituent have a significant yield. The catalyst can easily be recovered after completion of the reaction and reused without affecting its activity. Prepared benzimidazole derivatives showed moderate to good anti-tuberculosis results.
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