Multidisciplinary approaches to downstaging hepatocellular carcinoma: present and future

Autor: Sang-Youn Hwang, Hyunwook Choi, Wan Jeon, Ryoung-Go Kim
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Journal of Liver Cancer, Vol 24, Iss 2, Pp 171-177 (2024)
Druh dokumentu: article
ISSN: 2288-8128
2383-5001
DOI: 10.17998/jlc.2024.08.30
Popis: Downstaging of hepatocellular carcinoma (HCC) is typically defined as the reduction in size or number of viable tumors through locoregional therapy (LRT), aiming to meet the established criteria for liver transplantation (LT). According to the Barcelona Clinic Liver Cancer (BCLC) staging system, a subgroup of patients with BCLC-B may benefit most from downstaging therapies. The United Network Organ Sharing downstaging protocol identifies potential candidates for downstaging by setting out ‘inclusion criteria’ and defining ‘successful downstaging.’ Additionally, the protocol considers factors related to tumor biology, such as an alphafetoprotein level
Databáze: Directory of Open Access Journals