Genomic retargeting of p53 and CTCF is associated with transcriptional changes during oncogenic HRas-induced transformation

Autor: Michal Schwartz, Avital Sarusi Portugez, Bracha Zukerman Attia, Miriam Tannenbaum, Leslie Cohen, Olga Loza, Emily Chase, Yousef Turman, Tommy Kaplan, Zaidoun Salah, Ofir Hakim
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Communications Biology, Vol 3, Iss 1, Pp 1-13 (2020)
Druh dokumentu: article
ISSN: 2399-3642
DOI: 10.1038/s42003-020-01398-y
Popis: By integrating transcriptome, regulatory element and chromosome topology profiles, Schwartz et al identify redistribution of p53 and CTCF genomic binding to be associated with transcriptional and phenotypical changes during Ras-induced transformation of mammary epithelial cells.
Databáze: Directory of Open Access Journals
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