Antimicrobial Activity of Phytic Acid, Citric Acid, and EDTA with and without Propolis against Enterococcus Faecalis and Candida Albicans

Autor: Merve Yeniçeri Özata, Ömer Acer, Özlem Demirci, Mehmet Çolak, Gizem Akın Tartuk
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Journal of Dental Materials and Techniques, Vol 11, Iss 3, Pp 192-200 (2022)
Druh dokumentu: article
ISSN: 2322-4150
2252-0317
DOI: 10.22038/jdmt.2022.65976.1522
Popis: Introduction: This study aimed to investigate the antimicrobial efficacy of chelation agents on Enterococcus faecalis (E. faecalis) and Candida albicans (C. albicans) when used alone or in combination with propolis. Methods: One hundred fifty mandibular premolar teeth were selected. Each canal was prepared with Reciproc R25. The roots were then divided into two parts along their long axis (n=300). For E. faecalis and C. albicans, the samples were divided into 16 groups (14 experimental and 2 control) as follows: Group 1A-1B [17% Ethylenediaminetetraacetic acid (EDTA)], Group 2A-2B [10% Citric Acid (CA)], Group 3A-3B [1% phytic acid/inositol hexaphosphate (IP6)], Group 4A-4B (17% EDTA+8 mg/mL propolis), Group 5A-5B (10% CA+8 mg/mL propolis), Group 6A-6B (1% IP6+8mg/mL propolis), Group 7A-7B (8 mg/mL propolis), Control A-B (Dimethyl Sulfoxide). Each tooth was randomly irrigated with 2 mL of one of the group solutions or dispersions for 5 min, and the solutions were examined for the bactericidal effect. Results: For C. albicans, all groups showed less optical density (OD) than the control group (P0.05). Conclusion: CA and IP6 showed promising results in eliminating E. faecalis, one of the collective organisms responsible for failed root canals.
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