Antimicrobial peptide-coupled silver nanomaterials and their applications in medical and food fields

Autor: XIE Runsheng, LI Peijun, JIANG Yuqiu, CAO Xingye, LI Haiyun, SU Donglin
Jazyk: English<br />Chinese
Rok vydání: 2024
Předmět:
Zdroj: Shipin yu jixie, Vol 40, Iss 5, Pp 219-226 (2024)
Druh dokumentu: article
ISSN: 1003-5788
DOI: 10.13652/j.spjx.1003.5788.2024.60033
Popis: Due to antimicrobial activity, nanoparticles (NPs) in combination with antimicrobial peptides (AMPs) can be used to kill drug-resistant (MDR) pathogens. Nanosilver (AgNPs) has broad-spectrum and efficient antimicrobial properties, multiple bacterial inactivation mechanisms, and the ability to fine-tune the conjugation on the surface of antimicrobial peptide-conjugated silver nanoparticles (AMP-AgNPs), which results in higher biosafety of AMP-AgNPs. The review summarized the latest research progress of AMP-AgNPs conjugates and discussed the synthesis method, antibacterial activity, mechanism of action, hemolytic toxicity of AMP-AgNPs conjugates, as well as their applications in medical and food fields. The future development direction of AMP-AgNPs conjugates was also prospected.
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