Comparison of prognostic scales for patients with metastatic spine disease

Autor: Anton Denisov, Nikita S. Zaborovsky, Dmitry A. Ptashnikov, Dmitry A. Mikhailov, Sergey V. Masevnin, Oleg A. Smekalenkov
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Orthopedic Reviews, Vol 12, Iss 4 (2021)
Druh dokumentu: article
ISSN: 2035-8237
2035-8164
DOI: 10.4081/or.2020.8822
Popis: This is one-centre retrospective study with the aim to identify the scale, which provides the most accurate prediction of life expectancy in patients with metastatic lesions in spine. A retrospective analysis of clinical data of 138 patients with metastatic spinal tumors. Patients underwent spinal cord decompression and instrumented stabilization of affected area. We evaluated the general condition according to the Karnofsky and ECOG scales, the presence of metastases in the visceral organs, spine and other bones, the neurological status and conduction of the medical therapy before spinal surgery. Observed clinical parameters were converted to Tokuhashi, Tomita, and Katagiri scales. For statistical analysis, software environment R 3.4.1 was used. Assessment of prognostic accuracy was performed using ROC analysis. The Tokuhashi scale showed AUC 0.605 (95% CI 0.586-0.616), Tomita scale showed AUC 0.708 (95% CI 0.573-0.842), Katagiri scale showed AUC 0.650 (95% CI 0.508-0.792). The best results for survival rate predicting after surgical treatment for metastatic spinal lesions were shown the Tomita scale.
Databáze: Directory of Open Access Journals