| Autor: |
Hojat Dehghanbanadaki, Pooria Asili, Abdolkarim Haji Ghadery, Maryam Mirahmad, Ali Zare Dehnavi, Amirhossein Parsaei, Hamid Reza Baradaran, Mobin Azami, Gustavo Jose Justo da Silva, Reza Parvan, Yousef Moradi |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
BMC Medical Genomics, Vol 16, Iss 1, Pp 1-8 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
1755-8794 |
| DOI: |
10.1186/s12920-023-01476-0 |
| Popis: |
Abstract Background This study aimed to investigate the pooled diagnostic ability of circular RNA (circRNA) molecules for diabetes mellitus. Methods We searched PubMed, Scopus, and Web of Science for relevant studies. A total of 2070 participants, including 775 diabetic patients and 1295 healthy individuals, from five studies were included in this meta-analysis. True positive, true negative, false positive, and false negative data were extracted to calculate pooled sensitivity, specificity, positive and negative likelihood ratios, diagnostic odds ratio, and area under the receiver operating characteristics curve. The Deeks’ funnel plot was applied for publication bias assessment, Cochran’s Q test and I2 index were applied for inter-study heterogeneity assessment. Besides, a subgroup analysis was performed for determining the source of heterogeneity between studies. P value |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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