Impact of visit-to-visit variability in blood pressure on coronary plaque as assessed by integrated backscatter intravascular ultrasound

Autor: Yuta Kato, Atsushi Iwata, Makito Futami, Motoki Yamashita, Eiji Shigemoto, Takashi Kuwano, Makoto Sugihara, Shin-Ichiro Miura
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Clinical and Experimental Hypertension, Vol 42, Iss 7, Pp 608-613 (2020)
Druh dokumentu: article
ISSN: 1064-1963
1525-6006
10641963
DOI: 10.1080/10641963.2020.1756315
Popis: Introduction Visit-to-visit variability (VVV) in blood pressure (BP) has been reported to be a strong predictor of cardiovascular disease. However, the association between VVV in BP and coronary plaque composition has not been fully elucidated. Methods One hundred-two consecutive patients with coronary artery disease (CAD) who underwent percutaneous coronary intervention (PCI) using integrated backscatter (IB) intravascular ultrasound (IVUS), and who had at least six clinic visits a year before PCI were included. We measured systolic and diastolic BP (SBP and DBP) at each visit and determined VVV in BP expressed as the standard deviation of the average BP. Grayscale and IB IVUS examinations were performed for the culprit lesion of a coronary artery just before PCI. Results There were no significant associations between the average SBP or DBP and various IVUS parameters. However, VVV in SBP was positively correlated with both the percentage (%) of atheroma volume (β = 0.23, p = .02) and % lipid volume (β = 0.53, p
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