Spatio-temporal dynamics enhance cellular diversity, neuronal function and further maturation of human cerebral organoids

Autor: Pelin Saglam-Metiner, Utku Devamoglu, Yagmur Filiz, Soheil Akbari, Goze Beceren, Bakiye Goker, Burcu Yaldiz, Sena Yanasik, Cigir Biray Avci, Esra Erdal, Ozlem Yesil-Celiktas
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Communications Biology, Vol 6, Iss 1, Pp 1-18 (2023)
Druh dokumentu: article
ISSN: 2399-3642
DOI: 10.1038/s42003-023-04547-1
Popis: Two engineering approaches, a rotating cell culture system (RCCS) and microfluidic platform (µ-platform), are presented with the goal of improving harvestability, scalability, reproducibility and survival of human brain organoids in long term culture.
Databáze: Directory of Open Access Journals
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