| Autor: |
Sachiko Iwata, Reiji Katayama, Kennosuke Tsuda, Yung‐Chieh Lin, Tsuyoshi Kurata, Masahiro Kinoshita, Koya Kawase, Takenori Kato, Shin Kato, Tadashi Hisano, Motoki Oda, Etsuko Ohmae, Sachio Takashima, Yuko Araki, Shinji Saitoh, Osuke Iwata |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Annals of Clinical and Translational Neurology, Vol 9, Iss 9, Pp 1417-1427 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2328-9503 |
| DOI: |
10.1002/acn3.51641 |
| Popis: |
Abstract Objective MRI provides useful information regarding brain maturation and injury in newborn infants. However, MRI studies are generally restricted during acute phase, resulting in uncertainty around upstream clinical events responsible for subtle cerebral injuries. Time‐resolved near‐infrared spectroscopy non‐invasively provides the reduced scattering coefficient (μs′), which theoretically reflects tissue structural complexity. This study aimed to test whether μs′ values of the newborn head reflected MRI findings. Methods Between June 2009 and January 2015, 77 hospitalised newborn infants (31.7 ± 3.8 weeks gestation) were assessed at 38.8 ± 1.3 weeks post‐conceptional age. Associations of μs′ values with MRI scores, mean diffusivity and fractional anisotropy were assessed. Results Univariable analysis showed that μs′ values were associated with gestational week (p = 0.035; regression coefficient [B], 0.065; 95% confidence interval [CI], 0.005–0.125), fractional anisotropy in the cortical grey matter (p = 0.020; B, −5.994; 95%CI, −11.032 to −0.957), average diffusivity in the cortical grey matter (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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