Parvovirus B19 infections serological diagnostics in rheumatic diseases

Autor: L P Ananjeva, O A Koneva, S I Soldatova, S O Salugina, M. M. Urumova, D. E. Karateev, O. N. Egorova, E. Yu. Panasuk, N. V. Bunchuk
Jazyk: ruština
Rok vydání: 2005
Předmět:
Zdroj: Научно-практическая ревматология, Vol 43, Iss 4, Pp 18-23 (2005)
Druh dokumentu: article
ISSN: 1995-4484
1995-4492
DOI: 10.14412/1995-4484-2005-612
Popis: Objective. To study contamination with parvovirus B19 of a group of patients with rheumatic diseases (RD). Methods. 77 pts with RD (mean age 42,5 years, 79% female) admitted to Institute of Rheumatology of RAMS were examined. 34 of them had rheumatoid arthritis (RA), 11 - systemic lupus erythematosus (SLE) and Sjogren's disease (SD), 15 with osteoarthritis (OA) and seronegative spondyloarthritides (SS) and 17 with early (before a year) undifferentiated arthritis (EUA). Quantitative determination of IgM and IgG serum antibodies to parvovirus BI9 was performed by I FA with IBL kits (Hamburg, Germany). Results. Anti-B19 IgG antibodies were found in 52% of pts, IgM antibodies - only in one case. Mean antibodies values in pts with RD of disease duration less then 6 months were significantly higher then in pts with longer disease duration (21,5+36 U/ml and 8,4+14.7 U/ml respectively, p
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