| Autor: |
Yasuji Yoshikawa, Takashi Masuda |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Human Pathology: Case Reports, Vol 20, Iss , Pp 200373- (2020) |
| Druh dokumentu: |
article |
| ISSN: |
2214-3300 |
| DOI: |
10.1016/j.ehpc.2020.200373 |
| Popis: |
Neuroendocrine tumors (NETs) are rare in the gallbladder possibly because of paucity of the precursor neuroendocrine cells in this organ. Lipid-rich NET (LR-NET), also known as clear cell NET, is a rare but distinct variant of NET observed in various organs. In the gallbladder of the case reported herein, there was a pedunculated polypoid mass of golden-yellow in color which macroscopically mimicked a cholesterol polyp, albeit somewhat larger. Histologically the polyp showed accumulation of foamy lipid containing cells in the lamina propria covered by normal columnar epithelial cells, thus again resembling a cholesterol polyp. However, the foamy cells often showed ribbon-like arrangement and were immunohistochemically strongly positive for neuroendocrine markers. This report represents gross and microscopic features, including fat stain, of a peculiar type of LR-NET in the gallbladder. A rare but important differential diagnostic consideration in cholesterol polyp-like lesions seen on cholecystectomy specimens is presented. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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