Menstrual and Reproductive Factors in Association With Breast Cancer Risk in Vietnamese Women: A Case-Control Study
| Autor: | Oanh Thi Bui, Huong Thanh Tran, Sang Minh Nguyen, Tu Van Dao, Quang Vinh Bui, Anh Tuan Pham, Martha J. Shrubsole, Qiuyin Cai, Fei Ye, Wei Zheng, Hung Nguyen Luu, Thuan Van Tran, Xiao-Ou Shu |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Cancer Control, Vol 29 (2022) |
| Druh dokumentu: | article |
| ISSN: | 1073-2748 10732748 |
| DOI: | 10.1177/10732748221140206 |
| Popis: | Objectives Though menstrual and reproductive factors have been associated with the risk of breast cancer in many populations, very few studies have been conducted among Vietnamese women. This study aimed to assess the association between menstrual and reproductive factors and the risk of breast cancer in Vietnamese women. Methods A retrospective case-control study of 490 breast cancer cases and 468 controls was conducted in Northern Vietnam. Unconditional logistic regression models adjusting for confounders were used to estimate odds ratios (ORs) and their 95% confidence intervals (CIs) for the associations of menstrual and reproductive factors with the risk of breast cancer; overall and by cancer subtype. Results Among breast cancer patients, the luminal B subtype was the most frequent (48.6%), followed by HER2-overexpressing (24.5%), luminal A (16.7%), and triple-negative breast cancer (TNBC; 10.2%). Among menopausal women, menopausal age at 50 years or older (OR = 1.71, 95% CI: 1.15-2.57 vs. |
| Databáze: | Directory of Open Access Journals |
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